The Natural Selection Theory of Antibody Formation, in Proceedings of the National Academy of Sciences 55 No. 11 pp. 849 - 857, November 1955. [THEORY OF ANTIBODY FORMULATION, NOBEL PRIZE PAPER]
by Jerne, Niels K
- Used
- Paperback
- first
- Condition
- See description
- Seller
-
West Branch, Iowa, United States
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About This Item
National Academy of Sciences, 1955. 1st Edition. FIRST EDITION IN ORIGINAL WRAPS & HOUSED IN A CUSTOM PAMPHLET CASE of the groundbreaking theoretical paper by Niels K. Jerne describing his theory of antibody formulation. This article, which has 1,075 citations, revolutionized the theory of monoclonal antibodies and Jerne shared the 1984 Nobel Prize in Physiology or Medicine "for theories concerning the specificity in development and control of the immune system."
the Nobel Prize Committee awarded Jerne his prize, they did so noting that his "view of the nature of the immune system constitutes the basis for modern immunology" (Nobel Prize Committee) "Jerne's "natural-selection theory regarding antibody formation breaks with old views on the immune response and is a starting point of modern cellular immunology" (Nobel Prize Press Release).
Jerne "proposed that a broad range of specificities of antibodies were released into the blood spontaneously and that antibodies were subject to a replicative drive following their binding to antigen." In order to remain consistent with data indicating a cellular origin of antibody production, he postulated that on binding antigen, antibodies were shuttled to the appropriate cells for reproduction" (Pollard, Antibodies and autoimmunity, 46). CONDITION & DETAILS: November 1955 single issue in original wraps. Re-backed with original spine label. Housed in custom pamphlet cases. Very light library stamp on front wrapper, otherwise pristine. Bright and very clean throughout.
the Nobel Prize Committee awarded Jerne his prize, they did so noting that his "view of the nature of the immune system constitutes the basis for modern immunology" (Nobel Prize Committee) "Jerne's "natural-selection theory regarding antibody formation breaks with old views on the immune response and is a starting point of modern cellular immunology" (Nobel Prize Press Release).
Jerne "proposed that a broad range of specificities of antibodies were released into the blood spontaneously and that antibodies were subject to a replicative drive following their binding to antigen." In order to remain consistent with data indicating a cellular origin of antibody production, he postulated that on binding antigen, antibodies were shuttled to the appropriate cells for reproduction" (Pollard, Antibodies and autoimmunity, 46). CONDITION & DETAILS: November 1955 single issue in original wraps. Re-backed with original spine label. Housed in custom pamphlet cases. Very light library stamp on front wrapper, otherwise pristine. Bright and very clean throughout.
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Details
- Bookseller
- Atticus Rare Books (US)
- Bookseller's Inventory #
- 1623
- Title
- The Natural Selection Theory of Antibody Formation, in Proceedings of the National Academy of Sciences 55 No. 11 pp. 849 - 857, November 1955. [THEORY OF ANTIBODY FORMULATION, NOBEL PRIZE PAPER]
- Author
- Jerne, Niels K
- Book Condition
- Used
- Quantity Available
- 1
- Edition
- 1st Edition
- Binding
- Paperback
- Publisher
- National Academy of Sciences
- Date Published
- 1955
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About the Seller
Atticus Rare Books
Biblio member since 2010
West Branch, Iowa
About Atticus Rare Books
We specialize in rare and unusual antiquarian books in the sciences and the history of science. Additionally, we specialize in 20th century physics, mathematics, and astronomy.
Glossary
Some terminology that may be used in this description includes:
- First Edition
- In book collecting, the first edition is the earliest published form of a book. A book may have more than one first edition in...
- Re-backed
- Describes a book that has had the material covering the spine replaced or joints mended.
- Spine Label
- The paper or leather descriptive tag attached to the spine of the book, most commonly providing the title and author of the...